Fertility After Pediatric Cancer Treatment » Nursing Jobs Blog – Nurses Insights at Nursing Jobs.org

Fertility After Pediatric Cancer Treatment

February 16th, 2016  |  The Blog

An estimated 75% of children diagnosed with cancer survive into adulthood. The statistics are climbing higher but there is concern about children having children after cancer treatment. Their fertility is a real concern.

What Happens When Children Undergo Cancer Treatment?

Here are some facts about children undergoing cancer treatment:


Ovarian function is impaired. Specifically, the number of eggs within the ovaries is reduced, according to chief medical officer at Dana Farber/Boston Children’s Cancer and Blood Disorders Center, Dr. Lisa Diller. Basically, cancer treatment causes ovaries to age significantly. Those who have had cancer treatment and are now 20-years old, have the ovarian function of a 35 to 40-year old woman.


According to Dr. Richard Yu, MD, PhD, a urologist in Boston Children’s Hospital Department of Urology, chemotherapy and radiation used to treat childhood cancer can obliterate the sperm stem cells in the testes, much like the treatments affect a girl’s ovaries and eggs.

The Problem

The best case scenario would be for a child who is about to undergo treatment to bank their eggs or sperm. Patients diagnosed with cancer before puberty do not have mature eggs or sperm to bank before they begin cancer treatment.

Alternative Solutions Regarding Infertility?

Experimental procedures are in place as alternatives to banking eggs and sperm. For girls, ovarian tissue preservation and for boys, testicular tissue preservation is on the horizon. The effectiveness of both alternatives remains to be determined for the long-term.


The procedure to collect sperm stem cells, which can be re-implanted at a later time or stimulated to develop into mature sperm, is currently developed but still experimental.


Ovarian tissue preservation is more complicated than sperm stem cell preservation. The current downsides to this alternative solution are:

  • It is very experimental
  • It is invasive for the female child
  • The cost is prohibitive, in the thousands of dollars
  • Not all retrieved tissue survives the freezing process
  • It is an unknown time frame for how long the tissue can remain frozen
  • If any cancer cells are present in the tissue, it cannot be re-implanted because cancer could be reintroduced into the patient

There is an ovarian marker, anti-Mullerian hormone (AMH), which can indicate girls who are at high risk for infertility after cancer treatment. These girls would potentially reap the benefit of egg or ovarian tissue banking.

How AHM Works

AMH levels are lower if a child has longer or more aggressive cancer treatment. AMH is a good indicator of ovarian reserve in adult females and also helps to look at the fertility potential for pediatric patients.


Biopsies are used to identify new sperm stem cell markers. The hope of researchers is that cancerous cells and healthy cell can be separated and better procedures to coax stem cells to mature will be identified.

The Long-Term Outcome

By the time these pediatric patients are adults, the hope is that the technology linked to these experimental procedures to preserve future fertility will have evolved. There needs to be successful technology to:

  • Re-implant tissue
  • Stimulate tissue
  • Mature eggs in a lab without re-implanting
  • Mature sperm in a lab without re-implanting

For this alternative procedure to actually be effective and successful, the technology to reuse the frozen tissue needs to catch-up with the procedures used to retrieve them. If the technology evolves over the next 10 to 20 years, those patients who banked eggs or sperm will benefit greatly with regard to infertility. Without banking eggs or sperm, there will be little to no chance of fertility in the future. It is a gamble but one that some feel is worth risking.

About nburgess

No Responses to “Fertility After Pediatric Cancer Treatment”

  • Wholesale NHL Jerseys Cheap said on June 26th, 2017 at 11:16 pm

    The nearby agencies in most instances represent 5-10 carriers every obtaining you a great deal of quotes in no time at all!Now that you have found the best site for cheap car insurance, it is time to fill out the quote form. If they are all favorable, then hire the firm. There was an increase of near 50% in consumption of energy in the state. He has taken thousands of photographs and written millions of words about amateur golfers who played for the love of the game, not for money. Their focus is on building a team that excels together.

  • Wholesale Jerseys Cheap said on June 26th, 2017 at 11:18 pm

    Of course, the physical aspects of tennis training will also make one stronger and fitter.Let’s take an example from the horse racing section of my website to demonstrate this point.You are very welcome to visit the Foreclosure Listings Free website, where you can see a comparison of the top foreclosure listing services.  But above all, Jerry’s decorated service to our country in both World War II and Korea made him an integral part of the Greatest Generation.Whenever they have trouble locating the best electrician Orange County dwellers check the web.
    Wholesale Jerseys Cheap [url=http://www.cheapjerseyswholesalejerseys.us.com/]Wholesale Jerseys Cheap[/url]

  • Najlepsze plisy z montazem Lublin said on June 26th, 2017 at 11:57 pm

    Hey very nice website!! Guy .. Excellent ..
    Superb .. I will bookmark your site and take the feeds additionally?

    I am happy to seek out numerous helpful information here within the post, we need develop more techniques in this regard, thank you for sharing.
    . . . . .

  • Parenthood Season 6 on sale said on June 27th, 2017 at 1:54 am

    I have been surfing online more than 3 hours today, yet
    I never found any interesting article like yours.
    It’s pretty worth enough for me. In my view, if all webmasters and bloggers made good content as
    you did, the net will be a lot more useful than ever before.|
    I could not refrain from commenting. Very well written!|
    I’ll immediately grab your rss feed as I can’t to find your email subscription hyperlink or newsletter service.
    Do you’ve any? Please let me recognise in order
    that I may just subscribe. Thanks.|
    It is perfect time to make some plans for the future and it is time to be happy.
    I’ve read this post and if I could I want to suggest you few interesting things or tips.
    Maybe you could write next articles referring to this article.
    I desire to read even more things about it!|
    It’s perfect time to make a few plans for the future and it is time to be happy.
    I have learn this post and if I could I desire to recommend you
    some attention-grabbing things or suggestions. Maybe you can write
    subsequent articles regarding this article.

    I want to read more issues approximately it!|
    I have been browsing on-line greater than three hours today, but I
    by no means discovered any attention-grabbing article like yours.
    It is beautiful price enough for me. In my view, if all website
    owners and bloggers made good content material as you probably did,
    the internet can be a lot more useful than ever before.|
    Ahaa, its good conversation about this piece of writing here at
    this webpage, I have read all that, so now me also commenting at this place.|
    I am sure this piece of writing has touched all the internet users,
    its really really pleasant article on building up new weblog.|
    Wow, this paragraph is pleasant, my younger sister is analyzing these things, therefore I am going
    to let know her.|
    bookmarked!!, I love your site!|
    Way cool! Some very valid points! I appreciate you writing this write-up and also the rest of the website is very good.|
    Hi, I do believe this is a great blog. I stumbledupon it ;) I am going to return once
    again since i have book marked it. Money and freedom is the best way to change, may you be rich and continue to guide others.|
    Woah! I’m really enjoying the template/theme of this
    website. It’s simple, yet effective. A lot of times it’s challenging
    to get that “perfect balance” between superb usability and visual
    appearance. I must say you’ve done a fantastic job with this.
    In addition, the blog loads very fast for me on Opera. Excellent Blog!|
    These are genuinely impressive ideas in concerning blogging.
    You have touched some good points here. Any way keep up wrinting.|
    I enjoy what you guys are usually up too. This sort of clever work and
    coverage! Keep up the good works guys I’ve you
    guys to my personal blogroll.|
    Hi there! Someone in my Facebook group shared this website with us so I came to look it over.
    I’m definitely enjoying the information. I’m book-marking and
    will be tweeting this to my followers! Outstanding blog and great style and design.|
    I like what you guys tend to be up too. This
    type of clever work and exposure! Keep up the great works guys I’ve included you
    guys to my blogroll.|
    Hi there would you mind stating which blog platform you’re using?
    I’m planning to start my own blog in the near future
    but I’m having a hard time making a decision between BlogEngine/Wordpress/B2evolution and Drupal.
    The reason I ask is because your layout seems different then most blogs and I’m looking for something completely unique.
    P.S My apologies for getting off-topic but I had to ask!|
    Hello would you mind letting me know which web host you’re working with?
    I’ve loaded your blog in 3 completely different web browsers and I must
    say this blog loads a lot faster then most. Can you recommend
    a good internet hosting provider at a reasonable price?
    Thank you, I appreciate it!|
    I like it when individuals get together and share opinions.
    Great site, continue the good work!|
    Thank you for the good writeup. It in fact was a
    amusement account it. Look advanced to more added agreeable from you!
    By the way, how could we communicate?|
    Hey just wanted to give you a quick heads up.
    The text in your post seem to be running off the screen in Opera.
    I’m not sure if this is a formatting issue or something to do with internet browser compatibility but I figured I’d post to
    let you know. The design look great though! Hope you get the issue fixed soon. Cheers|
    This is a topic that’s close to my heart… Many thanks! Exactly where are your contact details though?|
    It’s very straightforward to find out any matter on web as compared to books, as I found this post at this site.|
    Does your blog have a contact page? I’m having trouble locating it but,
    I’d like to shoot you an e-mail. I’ve got some ideas for your blog you
    might be interested in hearing. Either way, great site and I look forward to
    seeing it develop over time.|
    Hi! I’ve been reading your weblog for a long time now
    and finally got the courage to go ahead and give you a
    shout out from Dallas Tx! Just wanted to tell you keep up the fantastic job!|
    Greetings from Idaho! I’m bored to death at work so
    I decided to browse your website on my iphone during
    lunch break. I really like the knowledge you provide here and can’t wait to take a look when I get home.
    I’m shocked at how quick your blog loaded on my mobile .. I’m
    not even using WIFI, just 3G .. Anyhow, wonderful blog!|
    Its such as you learn my thoughts! You appear to grasp a lot about
    this, like you wrote the e book in it or something.
    I believe that you can do with some % to
    pressure the message house a bit, however instead of that, that is excellent blog.

    A fantastic read. I will certainly be back.|
    I visited various blogs but the audio feature for
    audio songs present at this web page is in fact wonderful.|
    Hello, i read your blog occasionally and i own a similar one and i was
    just wondering if you get a lot of spam remarks? If so
    how do you protect against it, any plugin or anything
    you can suggest? I get so much lately it’s driving me insane so
    any support is very much appreciated.|
    Greetings! Very helpful advice in this particular article!
    It is the little changes that make the most significant changes.
    Thanks a lot for sharing!|
    I absolutely love your blog.. Pleasant colors & theme. Did you build this web
    site yourself? Please reply back as I’m trying to create my own blog and would like to know where you got this from or what the
    theme is called. Thanks!|
    Howdy! This post couldn’t be written much better! Looking at this post reminds me of my previous
    roommate! He continually kept preaching about this.
    I most certainly will forward this post to him. Pretty sure
    he’s going to have a good read. I appreciate you for sharing!|
    Wow! This blog looks exactly like my old one!

    It’s on a totally different subject but it has pretty much the same page layout and design. Superb choice of colors!|
    There’s certainly a great deal to learn about this topic. I love all the
    points you’ve made.|
    You have made some decent points there. I looked on the web
    for additional information about the issue and found most
    individuals will go along with your views on this site.|
    Hi, I check your new stuff like every week. Your writing style is witty, keep doing what you’re doing!|
    I just could not leave your web site before suggesting that I actually enjoyed
    the usual information a person provide for your guests?
    Is gonna be again frequently to investigate cross-check new posts|
    I needed to thank you for this wonderful read!! I certainly
    enjoyed every little bit of it. I have you book marked to check out new things
    you post_|
    Hi there, just wanted to say, I liked this article.

    It was inspiring. Keep on posting!|
    Hello, I enjoy reading through your article post. I like to write a little comment to support you.|
    I constantly spent my half an hour to read this blog’s articles daily along with a cup of coffee.|
    I constantly emailed this blog post page to all my associates, since
    if like to read it afterward my contacts will too.|
    My coder is trying to convince me to move to .net from PHP.
    I have always disliked the idea because of the costs.
    But he’s tryiong none the less. I’ve been using WordPress on a number of websites for about a year and am anxious
    about switching to another platform. I have heard great things
    about blogengine.net. Is there a way I can import all my wordpress content into it?
    Any help would be greatly appreciated!|
    Hi! I could have sworn I’ve been to this blog before but after browsing through some of the articles I realized it’s new to me.
    Anyways, I’m certainly delighted I stumbled upon it and I’ll be
    book-marking it and checking back often!|
    Great work! That is the kind of info that should be shared across the
    net. Shame on the search engines for no longer positioning this publish upper!

    Come on over and discuss with my web site . Thank you =)|
    Heya i’m for the first time here. I found this board and I
    find It really useful & it helped me out much. I hope to
    give something back and help others like you aided me.|
    Howdy, I do think your site may be having internet browser compatibility
    issues. When I look at your website in Safari, it looks fine but when opening in Internet
    Explorer, it has some overlapping issues. I simply wanted to provide you
    with a quick heads up! Besides that, great website!|
    Somebody necessarily help to make seriously articles I would state.
    This is the very first time I frequented your web page and thus far?
    I surprised with the research you made to create this particular publish amazing.

    Fantastic task!|
    Heya i’m for the first time here. I found this board and I in finding It really useful & it helped me out
    a lot. I’m hoping to present one thing back and aid others like you
    aided me.|
    Hey there! I simply would like to give you a huge thumbs
    up for your excellent information you’ve got right here on this post.
    I’ll be coming back to your blog for more soon.|
    I every time used to read article in news papers but now as I am a user
    of internet so from now I am using net for posts, thanks to web.|
    Your mode of explaining all in this paragraph is actually good, every one can easily know it, Thanks a lot.|
    Hello there, I found your blog via Google even as looking for a similar topic, your site
    got here up, it looks great. I’ve bookmarked it in my google bookmarks.

    Hello there, simply became aware of your blog via
    Google, and found that it’s truly informative. I’m gonna watch out for
    brussels. I will be grateful in case you proceed this in future.
    Numerous other people might be benefited from your writing.

    I’m curious to find out what blog platform you happen to be working with?

    I’m having some small security issues with my latest site and I would like to find something more safe.
    Do you have any recommendations?|
    I am extremely impressed with your writing skills and also with
    the layout on your blog. Is this a paid theme or did you modify it yourself?
    Either way keep up the excellent quality writing, it is rare to see a great blog like this one
    these days.|
    I am extremely inspired along with your writing skills as neatly as with the format
    in your weblog. Is this a paid subject matter or did you modify it
    your self? Either way keep up the excellent quality writing,
    it is rare to look a great blog like this one today..|
    Hi, Neat post. There is an issue with your site in web explorer, might check
    this? IE nonetheless is the marketplace chief
    and a huge part of folks will pass over your fantastic writing because of this problem.|
    I’m not sure where you’re getting your info, but good topic.
    I needs to spend some time learning more or understanding more.
    Thanks for fantastic information I was looking for this
    info for my mission.|
    Hi, i think that i saw you visited my blog so i came to _return the favor_.I’m attempting to find things to improve my web site!I suppose its ok to use {some of|a

  • Wholesale Nike NFL Jerseys China said on June 27th, 2017 at 3:44 am

    The second position split should be opened as far as you can go WITHOUT pain. It will help to toughen them up mentally. Don’t make this information up.”Everybody Wants To Follow This Method To Find Great Automobile Insurance RatesEverybody Wants To Follow This Method To Find Great Automobile Insurance RatesJune 5, 2012 | Author: Sally Rowe | Posted in InsuranceVehicle insurance is dictated in a lot each state and can be a necessity to drive legally. That was until 2002, when I discovered this relatively new betting company called Betfair, which introduced the completely innovative concept of person to person betting, cutting out the bookmaker completely.
    Wholesale Nike NFL Jerseys China

  • https://yasminwayne5806.wordpress.com said on June 27th, 2017 at 3:44 am

    Life Proficiency is a religious expertise where you are going to end up being totally acquainted with the internal processeses from your mind
    and body as well as know how you can create equipping practices
    that end up being instinctive patterns for a more essential as well as vitalized lifestyle.

  • Whether you’re still relatively brand new to Photoshop or even you are actually an advanced
    customer, there ensures to become procedures in this
    particular lesson you are going to intend
    to contribute to your mental toolbox.

  • Cheap NFL Jerseys Wholesale said on June 27th, 2017 at 4:59 am

    The following factor to do now that you know not to go inexpensive on coverage would be to get numerous insurance quotes. If you are going to use a free trial, browse the fine print. Technicians can recommend the best equipment to use. Therefore, what are you waiting for? Sign up for the first tennis lesson and you will not glance back again!. Regardless, it is inevitable that each NFL organization will attempt to make the smart moves in order to become the next Superbowl champions.

  • Wholesale NFL Jerseys China said on June 27th, 2017 at 5:15 am

    They have to do this if they want to get better quality out of their final product.”I can understand why people can be upset about me signing a contract and me having the kind of year I had,” he said. Store your investing expenses all the way down by staying away from money with pricey supervision charges and stockbrokers that bring large percentages in commissions.If you choosed apply in the home then you have to purchase everything that typically used in a salon. For FAQs, visit the related homepage at
    Wholesale NFL Jerseys China

  • Privacidade Sw said on June 27th, 2017 at 5:38 am

    Esse blog post ? assombroso. Revise em meu site que trata sobre constru??o.

  • Helo?sa said on June 27th, 2017 at 7:31 am

    Seu postagem realmente foi prodigioso. Olhe a meu blog que tem a tem?tica constru??o.

  • car computer chip said on June 27th, 2017 at 8:25 am

    Excellent goods from you, man. I have bear in mind your stuff previous to and you’re simply extremely fantastic.
    I actually like what you have acquired right here, certainly
    like what you’re saying and the way in which by which you are saying
    it. You make it entertaining and you still
    care for to stay it smart. I can’t wait to learn much
    more from you. This is actually a terrific web site.

  • Cheap Jerseys said on June 27th, 2017 at 9:50 am

    Check also some of the projects he has handled in the past. It’s not for everyone, you do need a lot of discipline, but it is definitely possible.70 whether the horse won or lost.4 = 42. To those who camp, this should serve as mats that keep dirt away from tents.
    Cheap Jerseys

  • soi keo said on June 27th, 2017 at 10:09 am

    This is the perfect web site for everyone who wishes to understand this topic.
    You know so much its almost hard to argue with you (not that I
    personally will need to…HaHa). You certainly put a fresh
    spin on a topic which has been discussed for many years.
    Excellent stuff, just excellent!

  • Cheap China Jerseys said on June 27th, 2017 at 10:44 am

    Ben Cherington expressed “discipline” when the huge trade with Los Angeles was announced. You could now lay the FTSE up at 1.Everybody under the sun tends to make problems every so often.This is called virtual web hosting is simply what you ought to hold your company website. This could go a long way in addressing this matter.

  • http://www.thoupscomputers.com said on June 27th, 2017 at 11:07 am

    _________ ________. _______________ _________ ____.

  • visa for vietnam said on June 27th, 2017 at 12:04 pm

    I blopg frequently and I really appreciate your content.
    This great article has truly peaked my interest. I’m going tto book mark your blog and keep checking for neew information about once a week.
    I opted in for your Feed as well.

  • all wheel drive cars said on June 27th, 2017 at 12:34 pm

    This article is in fact a nice one it helps new the web visitors, who are wishing
    for blogging.

  • jingle bells said on June 27th, 2017 at 12:56 pm

    Excellent post. I was checking constantly this blog and I am impressed!

    Very helpful information specifically the last part :
    ) I care for such information much. I was looking for this particular information for a long time.
    Thank you and best of luck.

  • mail.yahoo.com login said on June 27th, 2017 at 2:24 pm

    An SMS message sent by having a messenger is delivered inside same manner
    an ordinary mobile-to-mobile text is. Created like a partner to
    Yahoo Rocket – Mail, Ymail was….

  • kjssofpp said on June 27th, 2017 at 5:56 pm

    Fertility After Pediatric Cancer Treatment ? Nursing Jobs Blog – Nurses Insights at Nursing Jobs.org
    kjssofpp http://www.gqy2o0n8c5ou5bh92rbf91802a4y0a43s.org/

  • real exam dumps said on June 27th, 2017 at 6:11 pm

    I think the admin of this site is really working hard for his site,
    for the reason that here every material is quality based

  • translation services atlanta said on June 27th, 2017 at 6:33 pm

    These are actually enormous ideas in concerning blogging.
    You have touched some nice points here. Any way keep up wrinting.

  • ortam.biz said on June 27th, 2017 at 6:41 pm

    I do not even know how I ended up here, but I
    thought this post was good. I do not know who you are but certainly you’re going to
    a famous blogger if you are not already ;) Cheers!

  • certified translation services boston said on June 27th, 2017 at 7:01 pm

    If you wish for to obtain a great deal from this paragraph then you have to apply such methods to your won weblog.

  • Celsa said on June 27th, 2017 at 7:56 pm

    I read this article completely about the comparison of most recent and earlier technologies,
    it’s awesome article.

  • https://www.smore.com/ said on June 27th, 2017 at 8:51 pm

    Thanks for making the honest attempt to write regarding this.
    It may be extremely helpful for me and my friends.

Add Your Comments

Copyright © 1999-2014 Nursing Jobs, LLC. All Rights Reserved.
Call 888.613.8844 (M-F, 7-5 Pacific)

Send a message